Hexaxim

Per 0.5 mL Pertussis (filamentous haemagglutinin 25 mcg; pertussis toxoid 25 mcg), diphtheria toxoid ≥20 IU, tetanus toxoid ≥40 IU, H. influenzae type b polysaccharide 12 mcg, poliovirus type 1 (Mahoney) 40 D-antigen units, poliovirus type 2 (MEF-1) 8 D-antigen units, poliovirus type 3 (Saukett) 32 D-antigen units, hepatitis B antigen 10 mcg

Protection against diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis & serious diseases caused by H. influenzae type b in childn ≥6 wk of age.

Inj via IM in the upper part of child's leg or upper arm. Primary vaccination 2 inj at an interval of 2 mth, or 3 inj at an interval of 1-2 mth (at least 4 wk apart). Booster After the 1st course of inj, administer a booster dose in accordance w/ local recommendations, at least 6 mth after the last dose of the 1st course.

Hypersensitivity to the active substances or excipients; to glutaraldehyde, formaldehyde, neomycin, streptomycin or polymyxin B; after previous administration of Hexaxim or any other vaccines containing diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B or Hib. Resp disorder or swelling of the face after administration of Hexaxim; severe reaction affecting the brain w/in 7 days of a prior dose of a pertussis vaccine (acellular or whole cell pertussis); uncontrolled condition or severe illness affecting the brain & nervous system or uncontrolled epilepsy.

Moderate or high temp or an acute illness (eg, fever, sore throat, cough, cold or flu); vaccination may need to be delayed until the child is better. Previous reactions/events after receiving a pertussis vaccine: Fever (≥40°C) w/in 48 hr not due to another identifiable cause; collapse or shock-like state w/ hypotonic-hyporesponsive episode w/in 48 hr of vaccination; persistent, inconsolable crying lasting ≥3 hr, occurring w/in 48 hr of vaccination; convulsions w/ or w/o fever, occurring w/in 3 days of vaccination. Previous Guillain-Barré syndrome or brachial neuritis after vaccination of tetanus toxoid. Patient under treatment that suppresses immune system or w/ disease that causes the weakness of the immune system; acute or chronic illness including chronic renal insufficiency or failure; undiagnosed illness of the brain or uncontrolled epilepsy; problem w/ the blood that cause easy bruising or bleeding for a long time after minor cuts. Contains phenylalanine that may be harmful in patients w/ phenylketonuria.

Serious allergic reactions. Anorexia; crying; somnolence; vomiting; pain, redness or swelling at the inj site; irritability; fever (temp ≥38°C). Prolonged crying; diarrhoea; inj site induration.

Can be given at the same time as other vaccines eg, pneumococcal vaccines, MMR vaccines, varicella vaccines, rotavirus vaccines or meningococcal vaccines. When given at the same time w/ other vaccines, Hexaxim will be given at different inj sites.

Vaccines, Antisera & Immunologicals

J07CA09 - diphtheria-haemophilus influenzae B-pertussis-poliomyelitis-tetanus-hepatitis B ; Belongs to the class of combined bacterial and viral vaccines.

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