Perform regular blood tests during treatment. Autoimmune disorder, autoimmune haemolysis. In case of blood transfusion, blood should have gone though irradiation. Patients who will undergo stem cells collection. Renal & hepatic impairment. Severe chronic lymphocytic leukaemia; tumor lysis syndrome. Monitor for unusual CNS effects & any changes to the skin. Fertile men & women must use a reliable form of contraception. Avoid live vaccinations during & after treatment. May influence the ability to drive & use machines. Pregnancy & lactation. Childn <18 yr. Elderly >65 yr.
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