Ecopain Contraindications

ECOPAIN Capsules 200 mg is contraindicated: in patients with severe heart failure and for the treatment of peri-operative pain in the setting of coronary artery bypass graft surgery.
Hypersensitivity to the active substance or to any of the excipients.
Known hypersensitivity to sulfonamides.
Active peptic ulceration or gastrointestinal (GI) bleeding.
Patients who have experienced asthma, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria or other allergic-type reactions after taking acetylsalicylic acid (aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors.
In pregnancy and in women of childbearing potential unless using an effective method of contraception. Celecoxib has been shown to cause malformations in the two animal species studied. The potential for human risk in pregnancy is unknown, but cannot be excluded.
Breast-feeding.
Severe hepatic dysfunction (serum albumin <25 g/L or Child-Pugh score ≥10).
Patients with estimated creatinine clearance <30 mL/min.
Inflammatory bowel disease.
Congestive heart failure (NYHA II-IV).
Established ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease.