Curosurf

Curosurf

Manufacturer:

Chiesi

Distributor:

Firma Chun Cheong
/
Zenfields
Concise Prescribing Info
Contents
Poractant alfa
Indications/Uses
Treatment of resp distress syndrome (RDS) in pre-term babies. Prophylactic use in premature infants at risk for RDS.
Dosage/Direction for Use
Intratracheal Rescue treatment 100-200 mg/kg (1.25-2.5 mL/kg) single dose. Additional doses of 100 mg/kg each 1 at about 12 hrly intervals for infants still requiring assisted ventilation & supplementary oxygen. Max total dose: 300-400 mg/kg. Prophylaxis 100-200 mg/kg (1.25-2.5 mL/kg) single dose w/in 15 min after birth. Further doses of 100 mg/kg can be given 6-12 hr after the 1st dose, then at 12 hrly intervals if necessary. Max total dose: 300-400 mg/kg.
Contraindications
Special Precautions
Stabilise the baby's general condition. Correction of acidosis, hypotension, anaemia, hypoglycaemia & hypothermia is recommended. Babies born following very prolonged rupture of the membranes (>3 wk) may not show optimal response. Administration to premature infants w/ renal or hepatic impairment has not been studied.
Adverse Reactions
Uncommon: Severe infection (sepsis); intracranial bleeding; pneumothorax.
MIMS Class
Other Drugs Acting on the Respiratory System
ATC Classification
R07AA02 - natural phospholipids ; Belongs to the class of lung surfactants. Used in the treatment of respiratory diseases.
Presentation/Packing
Form
Curosurf susp 120 mg/1.5 mL
Packing/Price
1.5 mL x 1's
Form
Curosurf susp 240 mg/3 mL
Packing/Price
3 mL x 1's
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