SC Max vol: 1.5 mL/inj. Adult ≥18 yr 1 mg/kg rounded to the nearest 10 mg up to a max dose of 90 mg, administered every 4 wk. Ped patient 1 to <18 yr, weighing <10 kg 1 mg/kg rounded to the nearest 1 mg, administered every 2 wk; weighing ≥10 kg 0.8 mg/kg rounded to the nearest 10 mg, administered every 2 wk up to a max dose of 90 mg.
View Crysvita overdosage for action to be taken in the event of an overdose.
Contraindications
Concomitant use w/ oral phosphate &/or active vit D analogs (eg, calcitriol, paricalcitol, doxercalciferol, calcifediol). When serum P is w/in or above the normal range for age. Patients w/ severe renal impairment or ESRD.
Hypersensitivity. Discontinue if serious hypersensitivity reactions occur. Hyperphosphatemia associated w/ increased risk of nephrocalcinosis. Administration may result in local inj site reactions. Discontinue oral phosphate &/or active vit D analogs (eg, calcitriol, paricalcitol, doxercalciferol, calcifediol) 1 wk prior to treatment initiation. Patients w/ renal impairment. Pregnancy & lactation. Ped <1 yr. Elderly ≥65 yr.
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