Corstat Indications/Uses

Treatment of coronary heart disease.
Patients with coronary heart disease with a plasma cholesterol level of ≥5.5 mmol/L, Corstat is used in the reducing the risks of the following conditions: mortality of patient; coronary death and non-fatal myocardial infarction; undergoing myocardial revascularisation procedures (coronary artery bypass) grafting and percutaneous transluminal angioplasty); and slow the progression of coronary atherosclerosis, including the development of new lesions and new total occlusions.
Hyperlipidaemia: As an adjunct to diet for reduction of elevated total cholesterol, LDL-cholesterol, apolipoprotein B and triglycerides in patients with primary hypercholesterolaemia, heterozygous familial hypercholesterolaemia or combined (mixed) hyperlipidaemia when response to diet and other non-pharmacological measures is inadequate. Corstat increases HDL-cholesterol and, therefore lowers the LDL/HDL and total cholesterol/HDL ratios. As with any cholesterol-lowering therapy, other modifiable risk factors should also be considered when treatment is started.
Homozygous Familial Hypercholesterolaemia: As an adjunct to diet and other non-dietary measures in reducing elevated total cholesterol, LDL-cholesterol and apolipoprotein B in patients with homozygous familial hypercholesterolaemia when response to these measures is inadequate.