Symptoms: Somnolence, tachycardia and headache have been reported with overdoses. A single acute ingestion of 160 mg produced no adverse effects.
In the event of overdosage, treatment, which should be started immediately, is symptomatic and supportive.
Treatment: Consider standard measures to remove any unabsorbed drug in the stomach eg, adsorption by activated charcoal administered as a slurry with water. The administration of gastric lavage should be considered. Physiologic saline solution is the lavage solution of choice, particularly in children. In adults, tap water can be used; however, as much as possible, the amount administered should be removed before the next instillation. Saline cathartics draw water into the bowel by osmosis and therefore may be valuable for their action in rapid dilution of bowel content. It is not known whether loratadine is dialysable. After emergency treatment, the patient should continue to be medically monitored.