Discontinue in case of HTN, tachycardia, palpitations or cardiac arrhythmias, nausea or any other neurological sign. Caution in patients w/ cardiac arrhythmias, HTN, history of MI, DM, bladder neck obstruction, +ve anamnesis of bronchospasm; patients w/ stenosing peptic ulcer, pyloroduodenal obstruction & obstruction of the vesical cervix. Concomitant use w/ digitalis; other sympathomimetics, including decongestants, anorexogenics or amphetamine-type psychostimulants, antihypertensives, TCAs & other antihistamines; ergot alkaloid vasoconstrictors. Not recommended w/ reversible MAOIs eg, linezolid (non-selective), moclobemide (MAO-A selective). Preferable to discontinue treatment 24 hr before anaesth. Discontinue at least 48 hr before skin tests. Rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase isomaltase insufficiency. Do not use in patients w/ renal or hepatic impairment; during pregnancy or breast-feeding; in elderly >60 yr. Pseudoephedrine: CNS stimulation w/ convulsions or CV collapse w/ accompanying hypotension, especially in childn, elderly, or in cases of overdose. Risk of acute generalized exanthematous pustulosis. Sympathomimetic effects eg, increased BP, tachycardia or manifestations of CNS excitation at the recommended dose. Risk of abuse; toxicity in increased doses; tolerance; depression following rapid w/drawal. +ve doping test.
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