Ciclosporin-Teva Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Some side effects could be serious: Tell the doctor straight away if the patient notices any of the following serious side effects: Like other medicines that act on the immune system, ciclosporin may influence the body's ability to fight against infection and may cause tumours or other cancers, particularly of the skin. Signs of infection might be fever or sore throat.
Changes in the sight, loss of coordination, being clumsy, memory loss, difficulty speaking or understanding what others say, and muscle weakness. These might be signs of an infection of the brain called progressive multifocal leukoencephalopathy.
Brain problems with signs such as seizures, confusion, feeling disorientated, being less responsive, personality changes, feeling agitated, sleeplessness, changes to sight, blindness, coma, paralysis of part or all of the body, stiff neck, loss of coordination with or without unusual speech or eye movements.
Swelling at the back of the eye. This may be associated with blurred vision. It may also affect the sight because of the higher pressure inside the head (benign intracranial hypertension).
Liver problems and damage with or without yellow skin and eyes, nausea, loss of appetite and dark urine.
Kidney problems which may greatly reduce the amount of urine produced.
Low level of red blood cells or platelets. The signs include pale skin, feeling tired, being breathless, having dark urine (this is a sign of the breakdown of red blood cells), bruising or bleeding with no obvious reasons, feeling confused, feeling disorientated, being less alert and having kidney problems.
Other side effects include: Very common side effects: These side effects may affect more than 1 in 10 people: Kidney problems; High blood pressure; Headache; Shaking of the body which cannot be control; Excessive growth of body and facial hair; High level of lipids in the blood.
If any of these affects the patient severely, tell the doctor.
Common side effects: These side effects may affect between 1 and 10 in every 100 people: Fits (seizures); Liver problems; High level of sugar in the blood; Tiredness; Loss of appetite; Nausea (feeling sick), vomiting, abdominal pain, constipation, diarrhoea; Excessive hair growth; Acne, hot flushes; Fever; Low level of white blood cells; Feeling numb or tingling; Pain in the muscles, muscle spasm; Stomach ulcer; Gum tissue overgrowing and covering the teeth; High level of uric acid or potassium in the blood, low levels of magnesium in the blood.
If any of these affects the patient severely, tell the doctor.
Uncommon side effects: These side effects may affect between 1 and 10 in every 1,000 people: Symptoms of brain disorders including sudden fits, mental confusion, sleeplessness, disorientation, disturbance of vision, unconsciousness, sense of weakness in the limbs, impaired movements; Rash; General swelling; Weight gain; Low level of red blood cells, low level of platelets in the blood which could increase the risk of bleeding.
If any of these affects the patient severely, tell the doctor.
Rare side effects: These side effects may affect between 1 and 10 in every 10,000 people: Nerve problems with numbness or tingling in fingers and toes; Inflammation of the pancreas with severe upper stomach pain; Muscle weakness, loss of muscle strength, pain in muscles of the legs or hands or anywhere in the body; Destruction of red blood cells, involving kidney problems with symptoms such as swelling of the face, stomach, hands and/or feet, decreased urination, breathing difficulty, chest pain, fits, unconsciousness; Changes in menstrual cycle, breast enlargement in men.
If any of these affects the patient severely, tell the doctor.
Very rare side effects: These side effects may affect between 1 and 10 in every 100,000 people: Swelling at the back of the eye which may be associated with an increase in pressure inside the head and eyesight disturbances.
If this affects the patient severely, tell the doctor.
Other side effects with frequency not known: Frequency cannot be estimated from the available data: Serious liver problems both with and without yellowing of the eyes or skin, nausea (feeling sick), loss of appetite, dark coloured urine, swelling of the face, feet, hands and/or the whole body; Bleeding underneath the skin or purple skin patched, sudden bleeding with no apparent cause; Migraine or severe headache often with feeling and being sick (nausea, vomiting) and being sensitive to light.
If any of these affects the patient severely, tell the doctor.
Reporting of side effects: If the patient gets any side effects, talk to the doctor or pharmacist. This includes any possible side effects not listed.
Additional side effects in children and adolescents: There are no additional side effects to be expected in children and adolescents compared to adults.