Adult Initially 2 tab. If no relief is obtained w/in ½ hr, 1 tab at half-hrly intervals. For subsequent attacks, the initial dose may be 3 tab. If pain persists, additional 1 tab at half-hrly intervals. Max daily dose: 6 tab. Max wkly dose: 10 tab. Childn 6-12 yr Initially 1 tab. Additional dose of 1 tab may be given twice only if required in the course of an attack. Max daily dose: 3 tab. Max wkly dose: 5 tab.
Avoid excessive or continued daily use. Drug-induced headaches during prolonged & uninterrupted treatment. May cause myocardial ischaemia or, in rare cases, infarction. Patients should be informed of the max doses allowed & 1st symptoms of overdosage (eg, hypoaesthesia, paresthesia in the fingers & toes, non-migraine-related nausea & vomiting, symptoms of myocardial ischaemia). May induce fibrotic changes if used excessively over years. Patients w/ mild to moderate hepatic impairment especially cholestatic patients.
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