Treatment of RA (including juvenile RA or Still's disease), ankylosing spondylitis, OA & other non-rheumatoid arthropathies. Treatment of non-articular rheumatic conditions including capsulitis, bursitis, tendonitis, tendosynovitis, low back pain & soft-tissue injuries eg, sprains & strains. Mild to moderate pain eg, dysmenorrhoea, dental & post-op pain. Symptomatic relief of headache including migraine.
Adult 1,200-1,800 mg daily in 3-4 divided doses. Maintenance dose: 600-1,200 mg daily. Dose may be increased in severe or acute conditions. Max dose: 2,400 mg in divided doses. Childn ≥7 kg 20 mg/kg in divided doses. Max: 40 mg/kg daily in divided doses in juvenile RA.
View Brumed overdosage for action to be taken in the event of an overdose.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to ibuprofen, aspirin or other NSAIDs. History of, or active peptic ulcer/haemorrhage. Bronchial asthma. Severe heart failure. Peri-operative pain treatment in the setting of CABG surgery. History of GI bleeding or perforation related to previous NSAIDs therapy.
Associated w/ serious liver injury. Increased risk of serious CV thrombotic events, MI, & stroke; serious GI adverse events. Renal papillary necrosis & other renal injury in long-term administration of NSAIDs. Not recommended in patients w/ advanced renal disease. Concomitant use w/ acetylsalicylic acid is not recommended. Pregnancy & lactation. Elderly. Not recommended for childn <7 kg.
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