Supraventricular tachycardia or non-compensatory sinus tachycardia Loading dose: 500 mcg/kg infused over 1 min, then maintenance of 50 mcg/kg/min for 4 min. If response is satisfactory, continue maintenance infusion. If response is unsatisfactory, give 2nd loading dose of 500 mcg/kg, followed by maintenance infusion of 100 mcg/kg/min for 4 min. If needed, procedure may be repeated 1-2 times (up to max of 3 loading doses), maintenance infusion may be increased by 50 mcg/kg/min each time (max: 200 mcg/kg/min). Maintenance infusion may be continued for up to 48 hr.
Peri-op tachycardia or HTN: Immediate control 1 mg/kg bolus dose over 30 sec, then infusion of 150 mcg/kg/min if necessary. Adjust as required to a max of 200 (tachycardia) or 300 (HTN) mcg/kg/min.
Gradual control 500 mcg/kg bolus dose over 1 min, then infusion of 50 mcg/kg/min for 4 min. Adjust as required to a max of 200 (tachycardia) or 300 (HTN) mcg/kg/min.