Flu-like symptoms (headache, muscle aches, chills, fever); headache. Loss of appetite; feeling weak & tired; difficulty sleeping; depression; flushing; runny nose; diarrhoea; nausea or vomiting; numbness or tingling of skin; rash, bruising of the skin; increased sweating, night sweats; muscle, joint, arms, legs or neck pain; muscle cramps, joint & muscle stiffness; pain, bruising & redness at inj site; changes to blood tests. Serious allergic reactions, depression, liver problems.