APO-go Caution For Usage

Incompatibilities: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.
Pre-filled syringe: Special precautions for disposal and other handling: APO-go PFS 5mg/ml Solution for Infusion in Pre-filled Syringe is for single use only. Any unused solution should be discarded.
After single use, adaptors and syringes should be discarded and disposed of in a "Sharps" bin.
Pre-filled pen: Instruction for use, handling and disposal: APO-go PEN: Do not use if solution has turned green.
Discard each pen no later than 48 hours from first use.
This pack does NOT contain needles for use with the Pen.
Use pen needles not more than 12mm (½") in length and not finer than 0.33mm (29 G). Pen needles recommended for use with insulin pens are compatible with APO-go Pen.
IMPORTANT: Do not pull the red capped dial before the dosage is set (see Selecting the correct dose as follows).
Attaching the needle: (a) Before using APO-go Pen, some surgical wipes and one needle in its protective cone will be needed.
(b) Take the Pen out of its box and remove the outer sleeve.
(c) Wipe the membrane of the Pen with a surgical wipe.
(d) Peel off the paper from the needle cone.
(e) It is important to bring the needle to the Pen in a straight line. If the needle is presented at an angle, it may cause the Pen to leak.
(f) Screw the cone clockwise onto the membrane until it is tight. This securely attaches the needle.
(g) Remove the protective cone, but do not throw it away. Do not remove the needle protector at this stage.
(h) Replace the Pen's outer sleeve.
Selecting the correct dose: (i) Press the red capped dosage dial and, whilst holding it down, turn the dial clockwise until the arrow points to the dose the doctor chose. Release the downward pressure on the red capped dial. The dose is now set and there is no need to redial for subsequent injections.
Important: If the prescribed dose is passed while turning the dial, just continue pressing and turning in the same direction until the arrow points to the dose the doctor chose.
Never pull and turn the red capped dosage dial at the same time.
If the dose is 1 mg, start by emptying a 1-mg dose onto a paper tissue and discarding it. This is called 'priming' and is important because it ensures a full dose is administered the first time the Pen is used. Then, set the dose required for injection and inject it in the usual way (see Injecting as follows). If the first dose required is more than 1 mg, there is no need to prime the Pen.
Injecting: (j) Once the dose is set, gently pull out the red capped dosage dial as far as it will go. Check the red scale on the plunger and inject only if the line that is just visible matches the intended dose.
(k) Using a surgical wipe, clean the area of skin where the medicine is planned to be injected and the area around it.
(l) Remove the Pen's outer sleeve.
(m) Remove the needle protector.
(n) Insert the needle into the skin as shown by the doctor.
(o) To inject, press the red capped dosage dial down as far as it will go, using the thumb if possible. Once the red capped dosage dial is fully depressed, count to three before withdrawing the needle.
(p) Replace the protective cone onto the used needle and push gently into place. Once secure, turn the needle anti-clockwise to unscrew it.
Keep the needle in its protective cone and discard it in a safe place, such as a "Sharps" bin or an empty coffee jar.
Preparing for the next injection: (q) Remove the outer sleeve of the Pen and check if there is enough apomorphine left in the cartridge for the next injection. If there is, put a new needle in place in the same way as before.
(r) If there is not enough apomorphine left for another injection, prepare another pen.
(s) Finally, replace the outer sleeve of the Pen.