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Chỉ định và Liều dùng
Oral
Adjuvant therapy in congestive heart failure Adult: Dose used in clinical trials: 0.5-3 g daily.
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Chống chỉ định
Hypersensitivity.
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Thận trọng
Renal failure.
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Tác dụng
Description:
Mechanism of Action: Taurine, 2-aminoethane sulfonic acid, is a conditionally essential amino acid derived from methionine and cysteine metabolism. Unlike true amino acids, it is not incorporated into proteins and is one of the most abundant free amino acids found in various tissues e.g. retina, brain, skeletal and cardiac muscles. It is involved in bile acid conjugation as well as other physiological functions e.g. detoxification, membrane stabilisation, osmoregulation and cellular calcium levels modulation. Some of the clinical uses investigated include use in CHF, cystic fibrosis, toxic exposure and liver disorders. Human breast milk are found to be rich in taurine. It is widely found in infant formula and parenteral nutrition of low-birth-wt infants due to the low biosynthetic capacity of the human neonate to produce taurine. |
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Phân loại MIMS
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Đăng xuất
