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Chỉ định và Liều dùng
Oral
Psychoses Adult: Acute and chronic psychoses: 400-800 mg daily. May also be given via IM inj.
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Suy thận
Dose reduction may be needed.
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Chống chỉ định
Comatose states, CNS depression, phaeochromocytoma, porphyria, bradycardia. Lactation.
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Thận trọng
Renal impairment, CV disease, Parkinson's disease, depression. Elderly. May impair ability to drive or operate machinery.
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Tác dụng không mong muốn
Extrapyramidal effects, parkinsonian symptoms, dystonia, akathesia, tardive dyskinesia, sleep disturbances, overstimulation, agitation, wt gain, sedation, hyperprolactinaemia.
Potentially Fatal: Ventricular arrhythmia e.g. torsade de pointes, neuroleptic malignant syndrome. |
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Tương tác
Increased risk of ventricular arrhythmia with drugs that prolong QT interval. Increased CNS depression with other CNS depressants e.g. alcohol, general anaesthetics, hypnotics, opioids.
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Tác dụng
Description:
Mechanism of Action: Sultopride has general properties similar to those of sulpiride. It is a dopamine antagonist and is used in the emergency management of agitation in patients who are psychotic or aggressive and in psychoses e.g. schizophrenia. Given as the hydrochloride but doses are expressed in terms of base. Sultopride hydrochloride 441 mg is equivalent to 400 mg sultopride. |
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Phân loại MIMS
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Đăng xuất
