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Chỉ định và Liều dùng
Intramuscular
Anaemia in chemotherapy patients Adult: 50-150 mg weekly. Intramuscular Anabolic after debilitating illness, Postmenopausal osteoporosis, Metastatic breast cancer Adult: As nandrolone decanoate: 25-100 mg once every 3-4 weeks. Intramuscular Anaemia of chronic renal failure Adult: As nandrolone decanoate: Female: 50-100 mg once weekly. Male: 100-200 mg once weekly. Discontinue if there is no improvement within 3-6 months.
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Chống chỉ định
Prostatic or breast carcinoma (male); nephrosis, porphyria; infants, pregnancy and lactation.
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Thận trọng
Monitor diabetic patients carefully. Conditions influenced by oedema (e.g. CV disease, migraine, seizure disorder, renal impairment). Hepatic impairment. Elderly. Discontinue if signs of virilisation in women occur. Monitor skeletal maturation in children.
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Tác dụng không mong muốn
Male: Postpubertal: Acne, gynaecomastia, bladder irritability, priapism, insomnia, chills, decreased libido, hepatic dysfunction, nausea, diarrhoea, prostatic hyperplasia. Prepubertal: Acne, virilism, chills, insomnia, hyperpigmentation, diarrhoea, nausea. Female: Virilism, hypercalcaemia, nausea, diarrhoea, chills, insomnia, iron deficiency anaemia, hepatic dysfunction.
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IM/Parenteral: X
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Tương tác
May increase effects of oral anticoagulants, insulin, oral antidiabetic agents, adrenal steroid, adrenocorticotropic hormone (ACTH).
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Ảnh hưởng đến kết quả xét nghiệm
May alter glucose tolerance tests.
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Tác dụng
Description:
Mechanism of Action: Nandrolone is an anabolic steroid. It promotes tissue-building processes and protein anabolism. It also stimulates erythropoeitin production, causing an increase in haemoglobin and RBC volume. Onset: 3-6 mth. Duration: Up to 30 days. Pharmacokinetics: Absorption: 77% (IM). Metabolism: Hepatic. Excretion: Via urine. |
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Phân loại MIMS
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Đăng xuất
