Melitracen

Oral
Depression

Preexisting CV insufficiency; severe liver disease; children; overactive patients.

Urinary retention, prostatic hypertrophy, untreated angle-closure glaucoma, pheochromocytoma; history of epilepsy; CV disease; impaired liver function; diabetes; risk of suicide; may precipitate mania or psychotic symptoms when used for CNS disorders; withdraw gradually; may impair ability to operate machinery. Pregnancy and lactation. Elderly.

Restlessness, insomnia, anticholinergic effects, tachycardia, orthostatic hypotension, drowsiness, GI upset, testicular enlargement, impotence. Withdrawal symptoms.

Additive toxicity with antimuscarinics, CNS depressants. Response to TCA may be accelerated with thyroid hormones; pressor effects of sympathomimetics may be enhanced; risk of serotonin syndrome when taken with other antidepressants. Antidiabetic dosage may need to be adjusted.

Description:
Mechanism of Action: Melitracen is a TCA with anxiolytic properties.

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