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Chỉ định và Liều dùng
Oral
Cholera, Giardiasis Adult: 100 mg 4 times daily. Usual duration: 2-5 days, up to 7 days in some patients or 10 days for giardiasis.
Child: 1.25 mg/kg 4 times daily, usually given for 2-5 days or up to 10 days for giardiasis. |
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Cách dùng
Should be taken with food. Avoid food & beverage containing tyramine or tryptophan, eg, alcohol, beer (including alcohol-free beer), cheese, yoghurt.
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Chống chỉ định
Hypersensitivity, infants <1 mth. Alcohol.
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Thận trọng
Pregnancy, lactation, G6PD deficiency.
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Tác dụng không mong muốn
Hypersensitivity, hypoglycaemia, orthostatic hypotension, dizziness, drowsiness, headache, malaise, nausea, vomiting, rash, fever, arthralgia, brown urine, haemolytic anaemia.
Potentially Fatal: Agranulocytosis. Hypertensive crisis with MAOIs. |
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Tương tác
Disulfiram-like reaction with alcohol. Potential hypertensive crisis with sympathomimetics, tyramine-containing foods, levodopa.
Potentially Fatal: Potentiation of MAOIs. Toxic psychosis with amitriptyline. |
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Tương tác với thức ăn
Reaction with foods rich in tyramine.
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Tác dụng
Description:
Mechanism of Action: Furazolidone has a broad antibacterial spectrum which is active against susceptible organisms including E. coli, staphylococci, Giardia sp. and against salmonella, shigella, proteus, and V. cholerae. Its bactericidal action is by interfering with bacterial enzyme systems. Pharmacokinetics: Absorption: Poor (oral). Excretion: Urine (as active drug and metabolites). |
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Phân loại MIMS
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Đăng xuất
