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Chỉ định và Liều dùng
Oral
Hypotensive states Adult: As hydrochloride: 5 or 10 mg tid. Modified-release dosage form: 25 mg once or bid.
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Chống chỉ định
Preexisting hypertension; occlusive vascular disease; pheochromocytoma; angle-closure glaucoma (eye drops); hypersensitivity; cardiac arrhythmias.
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Thận trọng
CV diseases; hyperthyroidism; diabetes mellitus; Parkinson's disease; elderly; pregnancy, lactation.
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Tác dụng không mong muốn
CNS effects; GI disturbances; epigastric pain; CV disorders; difficulty in micturition with urinary retention; dyspnoea; hyperglycaemia; sweating; hypersalivation; weakness, tremors; coldness of extremities; hypokalaemia; palpitations; tachycardia and arrhythmias.
Gangrene.
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Tương tác
Halogenated inhalation anaesthetics; β- or α-blocking agents; methyldopa, guanethidine; drugs with vasoconstrictor and pressor effects; antihypertensives; adrenergic neuron blockers; potassium-depleting drugs; cardiac glycosides; ephedra, yohimbe. TCAs may induce HTN and arrhythmia.
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Ảnh hưởng đến kết quả xét nghiệm
Increase in bilirubin, catecholamines, glucose, uric acid.
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Tác dụng
Description:
Mechanism of Action: Etilefrine is a direct-acting sympathomimetic with β1-agonist and some α- and β2-agonist actions. |
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Phân loại MIMS
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Đăng xuất
