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Chỉ định và Liều dùng
Oral
Allergic conditions Adult: 25-50 mg daily.
Elderly: Child: Same as adult dose. |
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Chống chỉ định
Urinary or GI tract obstruction, paralytic ileus. Pregnancy and lactation.
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Thận trọng
Patient w/ closed-angle glaucoma, prostate enlargement, heart disease, and epilepsy. Childn.
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Tác dụng không mong muốn
Headache, sleep disorder, hypotension, loss of appetite, asthma, bone marrow depression, constipation, drowsiness, increased sweating, tingling, shock, swelling, wt gain, urinary hesitancy, urinary retention, CNS depression, dry mouth, thickening of resp secretions, blurred vision, GI upset, tinnitus, vertigo, giddiness, nausea, paraesthesia, bradycardia followed by tachycardia and arrhythmias; paradoxical stimulation in childn.
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Thông tin tư vấn bệnh nhân
May impair ability to drive or operate machinery.
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Tương tác
Additive anti-muscarinic effect w/ MAOIs, TCAs and atropine. Enhances the CNS depressant effect of barbiturates, sedatives, hypnotics, analgesics and neuroleptics. Masks ototoxicity produced by aminoglycosides.
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Tương tác với thức ăn
Enhances the CNS depressant effect of alcohol.
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Tác dụng
Description:
Mechanism of Action: Embramine selectively binds to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. |
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Bảo quản
Store at room temp.
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Phân loại MIMS
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Tài liệu tham khảo
Buckingham R (ed). Embramine Hydrochloride. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 15/04/2016. Embramine. National Center for Biotechnology Information. PubChem Database. https://pubchem.ncbi.nlm.nih.gov/. Accessed 15/04/2016 . Mebryl (GlaxoSmithKline). MIMS India. http://www.mims.com/india. Accessed 15/04/2016 .
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