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Chỉ định và Liều dùng
Oral
Mucolytic Adult: As treatment of bronchopulmonary diseases associated with abnormal mucus secretion and clearance: As cap: 200 mg bid. As syr: 80-160 mg bid.
Child: >2 years As syr: 80 mg bid. |
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Cách dùng
May be taken with or without food.
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Thận trọng
Severe renal impairment. Children.
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Tác dụng không mong muốn
Gastrointestinal disorders: Nausea.
Respiratory, thoracic and mediastinal disorders: Bronchial obstruction. |
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Tác dụng
Description:
Mechanism of Action: Cyclidrol is a mucolytic that decreases the viscosity of mucus, facilitates the removal of mucus and mucopurulent secretions from the respiratory tract. Synonym(s): Sobrerol. Pharmacokinetics: Absorption: Rapidly absorbed from the gastrointestinal tract. Distribution: Rapidly and widely distributed to peripheral compartment. Excretion: Via urine (23.36% as free cyclidrol, glucuronic acid-conjugated cyclidrol and hydrated carvone). |
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Đặc tính
 Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 91463, Sobrerol. https://pubchem.ncbi.nlm.nih.gov/compound/Sobrerol. Accessed Nov. 23, 2023. |
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Bảo quản
Store below 25°C.
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Phân loại MIMS
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Tài liệu tham khảo
Anon. Sobrerol. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 04/09/2023. Buckingham R (ed). Sobrerol. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 04/09/2023. Mucoflux Capsules/Syrup (Mylan Healthcare Sdn. Bhd.). National Pharmaceutical Regulatory Agency - Ministry of Health Malaysia. https://www.npra.gov.my. Accessed 04/09/2023.
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