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Chỉ định và Liều dùng
Oral
Susceptible infections Adult: 500 mg bid.
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Chống chỉ định
Hypersensitivity to cephalosporins.
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Thận trọng
Hypersensitivity to penicillins; renal impairment; porphyria. Monitor renal and hematologic status. Pregnancy, lactation.
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Tác dụng không mong muốn
Nausea; vomiting; diarrhoea; hypersensitivity reactions; nephrotoxicity; convulsions; CNS toxicity; pseudomembranous colitis; hepatic dysfunction; haematologic disorders; pain at Inj site (IM); thrombophloebitis (IV infusion); superinfection with prolonged use.
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Tương tác
Renal excretion delayed by probenecid. Decreases contraceptive effect of estrogen-containing oral contraceptives.
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Ảnh hưởng đến kết quả xét nghiệm
Positive direct antiglobulin Coombs' test; falsely high values with Jaffe method of measuring creatinine concentrations; +ve reactions for false glucose using copper-reduction reactions; transient increases in liver enzyme values.
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Tác dụng
Description:
Mechanism of Action: Cefatrizine inhibits final cross-linking stage of peptidoglycan production thus inhibiting bacterial cell wall synthesis. It has excellent activity against gram-positive cocci except enterococci at minimal inhibitory concentrations <1 mcg/ml. |
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Phân loại MIMS
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Đăng xuất
