Dexbrompheniramine


Generic Medicine Info
Indications and Dosage
Oral
Allergic conditions
Adult: In combination with decongestant, pseudoephedrine: 2 mg up to 4 times daily.
Child: >6 yr: In combination with pseudoephedrine, 1 mg up to 4 times daily.
Contraindications
Severe liver disease; premature infants or full-term neonates.
Special Precautions
Pregnancy; lactation; severe CV disorders; asthma; avoid alcohol; drowsiness; angle-closure glaucoma, urinary retention, prostatic hypertrophy, pyloroduodenal obstruction; renal and hepatic impairment; elderly; epilepsy.
Adverse Reactions
Sedation; antimuscarinic effects, CNS depression and disturbances; occasionally, paradoxical CNS stimulation; psychomotor impairment; headache; palpitations and arrhythmias; convulsions, sweating, myalgia, paraesthesias, extrapyramidal symptoms, tremor; sleep and GI disturbances; hypersensitivity reactions and blood disorders; tinnitus, hypotension; hair loss. Withdrawal symptoms following long-term therapy.
Drug Interactions
CNS depressants eg, alcohol, barbiturates, hypnotics, opioid analgesics, anxiolytic sedatives and neuroleptics; other antimuscarinics; MAOIs; betahistine; ototoxic drugs.
Lab Interference
May interfere with skin testing.
Action
Description:
Mechanism of Action: Dexbrompheniramine is an antihistamine with antimuscarinic and moderate sedative actions.
MIMS Class
Antihistamines & Antiallergics
Disclaimer: This information is independently developed by MIMS based on Dexbrompheniramine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com
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