Neutropenia following bone marrow transplantation
Adult: 150 mcg/m2 (19.2 million IU/m2) daily given via IV infusion over 30 minutes or via SC inj, to be started the day (not less than 24 hours) after transplantation and continued until the expected nadir has passed and the neutrophil count has stabilised. Max duration: 28 days.
Child: >2 years Same as adult dose.
Child: >2 years Same as adult dose.
Subcutaneous
Mobilisation of peripheral blood progenitor cells for autologous peripheral blood stem cell transplantation
Adult: As monotherapy: 10 mcg/kg (1.28 million IU/kg) daily for 4-6 days (5-6 days in healthy donors). After myelosuppressive chemotherapy: 150 mcg/m2 (19.2 million IU/m2) daily, to be started 1-5 days after completion of chemotherapy and continued until the neutrophil count has stabilised.
Subcutaneous
Chemotherapy-induced neutropenia
Adult: 150 mcg/m2 (19.2 million IU/m2) daily, to be started on the day (not less than 24 hours) after the last dose of antineoplastic and continued until the expected nadir has passed and the neutrophil count has stabilised. Max duration: 28 days.
Child: >2 years Same as adult dose.
Child: >2 years Same as adult dose.