Zefuxim Dosage & Drug Information

Concise Prescribing Info

Contents

Cefuroxime Na

Indications/Uses

Alternative drug for infections due to susceptible organisms eg, otitis media, orbital cellulitis, UTI, skin & soft tissue, bone & joint infection & post-splenectomy sepsis of unclear etiology.

Dosage/Direction for Use

Adult 750 mg 8 hrly Severe infection 1.5 g IV 6-8 hrly. Infant & childn 25-100 mg/kg in 3-4 divided doses. Most infection 60 mg/kg/day. Neonate 30-100 mg/kg/day in 2 or 3 divided dose in the 1st wk of life. Gonorrhea 1.5 g as single dose. Meningitis Adult 3 g IV 8 hrly. Infant & childn 200-240 mg/kg daily IV in 3 or 4 divided dose, may be decreased to 100 mg/kg daily after 3 days. Neonate Initially 100 mg/kg/day IV, may be reduced to 50 mg/kg/day IV.

Contraindications

Hypersensitivity to penicillins or cephalosporins.

Special Precautions

Patients w/ GI disease particularly colitis, Clostridium difficile-associated diarrhea & colitis. Pregnancy.

Adverse Reactions

Skin rash, urticaria, eosinophilia, fever, serum-sickness reactions, anaphylaxis.

View ADR Monitoring Form

Drug Interactions

Aminoglycosides, probenecid.

MIMS Class

Cephalosporins

ATC Classification

J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Zefuxim powd for inj 1.5 g

Packing/Price

(vial + 10 mL diluent) 1's;10 × 1's

Form

Zefuxim powd for inj 250 mg

Packing/Price

(vial + 5 mL diluent) 1's;10 × 1's

Form

Zefuxim powd for inj 750 mg

Packing/Price

10 × 1's;1's

Zefuxim

cefuroxime

Manufacturer:

Singapore Pharmawealth Lifesciences

Distributor:

Singapore Pharmawealth Lifesciences