Provestin Dosage & Drug Information

Concise Prescribing Info

Contents

Medroxyprogesterone acetate

Indications/Uses

Listed in Dosage.

Dosage/Direction for Use

IM Mild to moderate endometriosis 50 mg wkly or 100 mg 2 wkly. Primary & secondary amenorrhagia 5-10 mg daily for 5-10 days until 2 days before anticipated onset of menstruation. Breast carcinoma 500 mg to 1 g daily twice wkly. Endometrial & renal carcinoma 250 mg-1 g wkly. Prostatic carcinoma 500 mg once/twice wkly. Contraception monotherapy 150 mg 12 wkly, combined therapy 25 mg w/ estradiol cipionate 5 mg mthly.

Contraindications

Thrombophlebitis, thromboembolic disturbances, severe hepatic insufficiency, breast carcinoma, undiagnosed vag bleeding, missed abortion.

Special Precautions

CV or renal impairment, DM, asthma, epilepsy & migraine, other conditions aggravated by fluid retention. Depression, high risk of arterial disease.

Adverse Reactions

GI disturbances, appetite or wt changes, fluid retention, edema, acne, chloasma (melasma), allergic skin rashes, urticaria, mental depression, breast changes/discomfort.

View ADR Monitoring Form

Drug Interactions

Aminoglutethimide.

MIMS Class

Oestrogens, Progesterones & Related Synthetic Drugs

ATC Classification

G03AC06 - medroxyprogesterone ; Belongs to the class of progestogens. Used as systemic contraceptives.

Regulatory Classification

Presentation/Packing

Form

Provestin susp for inj 50 mg/mL

Packing/Price

3 mL x 10 × 1's

Provestin

medroxyprogesterone

Manufacturer:

LBS

Distributor:

International Apex