Klornik Dosage & Drug Information

Concise Prescribing Info

Contents

Chloramphenicol Na succinate

Indications/Uses

Treatment of infections caused by gm +ve & gm -ve organisms.

Dosage/Direction for Use

Adult & childn 50 mg/kg in divided doses 6 hrly. Meningitis or severe infections Up to 100 mg/kg/day. Rickettsial diseases Continue 4 days after temp is normal. Typhoid fever 8-10 days. Full-term infant >2 wk 50 mg/kg daily in 4 divided doses. Premature & full-term neonate 25 mg/kg daily.

Contraindications

Hypersensitivity to chloramphenicols. Minor infections or prophylaxis. Pregnancy & lactation.

Special Precautions

Conduct adequate blood studies. Avoid repeated courses & prolonged treatment in newborn infants. Impaired liver function.

Adverse Reactions

Bone marrow depression characterized by decreased iron utilization, reticulocytopenia, leukopenia & thrombocytopenia. Aplastic anemia, hemolytic anemia, Gray baby syndrome, peripheral & optic neuritis.

View ADR Monitoring Form

Drug Interactions

Paracetamol, phenobarb, phenytoin or rifampicin. Coumarin anticoagulants, some hypoglycemic agents & antiepileptics. Alcohol.

MIMS Class

Chloramphenicols

ATC Classification

D06AX02 - chloramphenicol ; Belongs to the class of other topical antibiotics used in the treatment of dermatological diseases.

Regulatory Classification

Presentation/Packing

Form

Klornik powd for inj 1 g

Packing/Price

10 mL x 10 × 1's

Klornik

chloramphenicol

Manufacturer:

Swiss Parenterals

Distributor:

Endure Medical