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Zifex Plus

Zifex Plus

Manufacturer:

Zifam Pinnacle

Distributor:

Pinnacle House
Concise Prescribing Info
Contents
Per tab Cefixime trihydrate 200 mg, K clavulanate 125 mg. Per 5 mL syr Cefixime trihydrate 50 mg, K clavulanate 31.25 mg
Indications/Uses
Treatment of infections eg UTI, otitis media, pharyngitis, tonsillitis, acute bronchitis & acute exacerbations of chronic bronchitis, gonorrhoea (cervical/urethral), typhoid fever.
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Dosage/Direction for Use
Adult 1 tab bd for 7-14 days. Childn 8 mg/kg/day as a single dose or in 2 divided doses, >12 yr (>50 kg) Same as adult dose, 5 yr 7.5 mL bd, 3 yr 6 mL bd, 2 yr 5 mL bd, 1 yr 4 mL bd, 6 mth 2.5 mL bd.
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Overdosage
View Zifex Plus overdosage for action to be taken in the event of an overdose.
Contraindications
Hypersensitivity to cephalosporins.
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Warnings
For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Zifex Plus detailed prescribing information
Special Precautions
Hypersensitivity to penicillins. History of GI disease particularly colitis. Concomitant anticoagulant therapy. Renal impairment. Patients undergoing continuous ambulatory peritoneal dialysis & hemodialysis. Pregnancy & lactation. Childn <6 mth.
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Adverse Reactions
Diarrhea, loose stools, abdominal pain, dyspepsia, nausea & vomiting; skin rashes, urticaria, drug fever & pruritus, erythema multiforme, Stevens-Johnson syndrome & serum sickness-like reactions; transient elevations in SGPT, SGOT & alkaline phosphatase, BUN, creatinine; headache, dizziness; transient thrombocytopenia, leukopenia & eosinophilia; genital pruritus, vaginitis & candidiasis.
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Drug Interactions
Increased carbamazepine levels.
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Storage
View Zifex Plus storage conditions for details to ensure optimal shelf-life.
Description
View Zifex Plus description for details of the chemical structure and excipients (inactive components).
Action
View Zifex Plus mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Cephalosporins
ATC Classification
J01DD08 - cefixime ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Zifex Plus dry syr 81.25 mg/5 mL
Packing/Price
30 mL x 1's
Form
Zifex Plus tab 325 mg
Packing/Price
10's
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