Generic Medicine Info
Indications and Dosage
Allergic conjunctivitis
Adult: As 0.5% drops: Instill 4 times daily.

Allergic rhinitis, Asthma prophylaxis, Eczema, Hypertrophic scar, Keloid scar
Adult: 100 mg tid.
Child: 5 mg/kg/day in 3 divided doses.
Special Precautions
Not intended for treatment of acute asthma attacks. Renal and hepatic impairment.
Adverse Reactions
GI disturbances, headache, dizziness, drowsiness or insomnia, malaise, skin rashes and generalised pruritus; irritation and blepharitis. Rarely, liver function disturbance or jaundice, renal dysfunction, cystitis-like symptoms, anaemia, thrombocytopenia, leucopenia, palpitations, oedema, facial flushing, and stomatitis.
Monitoring Parameters
Haematological monitoring is advisable.
Description: Tranilast has a stabilising action on mast cells and also inhibits collagen synthesis in fibroblasts.
Chemical Structure

Chemical Structure Image

Source: National Center for Biotechnology Information. PubChem Database. Tranilast, CID=5282230, (accessed on Jan. 23, 2020)

MIMS Class
Antiasthmatic & COPD Preparations / Antihistamines & Antiallergics
Rogosnitzky M, Danks R, and Kardash E. Therapeutic Potential of Tranilast, an Anti-Allergy Drug, in Proliferative Disorders. Anticancer Res. 2012 Jul;32(7):2471-8. Accessed 16/09/2014. PMID: 22753703

Buckingham R (ed). Tranilast. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. Accessed 16/09/2014.

Disclaimer: This information is independently developed by MIMS based on Tranilast from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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