Cases of CHF may develop in combination w/ thiazolidinediones, especially in patients w/ risk factors for development of CHF. Oral antidiabetic products, MAOIs, β-blockers, ACE-inhibitors, salicylates, anabolic steroids & sulfonamides may reduce insulin requirement. OCs, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone & danazol may increase insulin requirements. Octreotide or lanreotide may either increase or decrease the insulin requirement. β-blockers may mask hypoglycemic symptoms. Alcohol may intensify or reduce the hypoglycaemic effect.