Medi-α 0.25: Each softgel capsule contains Alfacalcidol BP 0.25 micrograms.
Medi-α 1: Each softgel capsule contains Alfacalcidol BP 1 microgram.
Alfacalcidol or 1-α-hydroxyvitamin D3 is one of vitamin D analogue. Alfacalcidol is rapidly converted in liver to 1, 25-dihydroxyvitamin D3 {1, 25-(OH)2D3}, the metabolite of vitamin D3 which acts as a regulator of calcium and phosphate metabolism.
Impaired endogenous production of 1, 25-dihydroxyvitamin D3 by the kidneys appears to contribute to the disturbances in mineral metabolism found in several disorders, including renal bone disease hypoparathyroidism and vitamin D-dependent rickets. These disorders require high doses of vitamin D for their correction.
Osteoporosis; Renal osteodystrophy; Hypoparathyroidism; Hyperparathyroidism with bone disease; Nutritional and malabsorptive rickets and osteomalacia; Hypophosphataemic vitamin D-resistant rickets and osteomalacia.
Initial Dose: Adults & children: >20 kg body weight: 0.5-1 μg/day, <20 kg body weight: 0.05 μg/kg/day.
The dosage of Medi-α 0.25 / Medi-α 1 should be adjusted, thereafter to avoid hypercalcemia according to the biochemical response.
Hypercalcemia, Hypermagnesemia.
Hypersensitivity to Vitamin D or its analogues.
If the patient is pregnant or breastfeeding, inform the physician prior to the commencement of therapy with this medicine.
Store below 25°C in a dry place.
A11CC03 - alfacalcidol ; Belongs to the class of vitamin D and analogues. Used as dietary supplements.
Softgel cap 0.25 mcg x 6 x 5's, 10 x 10's. 1 mcg x 6 x 5's, 10 x 10's.
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