HTN Initially 5 mg once daily. Maintenance dose: 5 or 10 mg once daily. Dose can be decreased to 2.5 mg daily or increased at interval of at least 2 wk to 10 mg daily depending on patient's response. Elderly Initially 2.5 mg daily. Angina pectoris Initially 5 mg once daily, may be increased to 10 mg once daily if needed.
Patients w/ pronounced gingivitis/periodontitis. May precipitate significant hypotension which may result in myocardial ischaemia. Avoid concomitant use w/ strong CYP3A4 inducers or inhibitors. Minor or moderate influence on ability to drive & use machines.
C08CA02 - felodipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.