Choline theophyllinate

Generic Medicine Info
Indications and Dosage
Reversible airways obstruction
Adult: Initially, 0.2-0.4 g daily and increase gradually according to response. Maintenance: 0.8-1.2 g daily in 3-4 divided doses.
Child: 10-14 yrs: 400-800 mg in 4 divided doses; 5-9 yrs: 200-400 mg in 4 divided doses; <5 yrs: 24-36 mg/kg body weight/day in 3 divided doses.
Special Precautions
Peptic ulceration, hyperthyroidism, hypertension, cardiac arrhythmias or other CV diseases, epilepsy, hepatic dysfunction, chronic alcoholism, acute febrile illness; smoking; neonates; elderly; pregnancy, lactation.
Adverse Reactions
GI irritation and disturbances, CNS stimulation, headache, anxiety, restlessness, dizziness, tremor, palpitations.
Drug Interactions
Xanthines (additive effects), allopurinol, some antiarrhythmics, cimetidine, disulfiram, fluvoxamine, interferon-α, macrolide antibacterials, quinolones, oral contraceptives, tiabendazole, viloxazine, anticonvulsants, ritonavir, rifampicin, sulfinpyrazone, halothane, ketamine, β-blockers.
Description: Choline theophyllinate is a theophylline salt which liberates theophylline in the body. It inhibits the activity of phosphodiesterase, resulting in the intracellular accumulation of cyclic adenosine monophosphate (cAMP), thus leading to bronchodilation.
MIMS Class
Antiasthmatic & COPD Preparations
Disclaimer: This information is independently developed by MIMS based on Choline theophyllinate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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