Bromopride: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Myanmar prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Gastrointestinal motility disorders, Nausea and vomiting

Adult: 20-60 mg daily in divided doses.

Parenteral
Gastrointestinal motility disorders, Nausea and vomiting

Adult: IV/IM: 20 mg daily.

Contraindications

GI haemorrhage, obstruction, perforation or immediately after surgery. Patients with pheochromocytoma.

Special Precautions

Children, young patients, elderly; renal impairment, epilepsy, Parkinson's disease; history of depression. May impair ability to drive or operate machinery.

Adverse Reactions

Extrapyramidal symptoms; restlessness, drowsiness, diarrhoea; hypotension, hypertension, dizziness, headache, depression; galactorrhoea.
Potentially Fatal: Neuroleptic malignant syndrome.

Drug Interactions

Other centrally active drugs and those with extrapyramidal effects. Increased toxicity with lithium. Antagonism of GI effects with antimuscarinics and opioid analgesics. May affect absorption of other drugs.

Lab Interference

Transient increase in plasma-aldosterone concentration.

Action

Description: Bromopride is a substituted benzamide with prokinetic and antiemetic properties.

MIMS Class

GIT Regulators, Antiflatulents & Anti-Inflammatories

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