Zoladex LA Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage Patient Counseling Information MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Goserelin acetate

Indications/Uses

Management of prostate cancer suitable for hormonal manipulation; estrogen-receptor +ve breast cancer in premenopausal women.

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Dosage/Direction for Use

Adult including elderly 1 depot SC inj into anterior abdominal wall every 12 wk.

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Overdosage

View Zoladex LA overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity.

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Special Precautions

Increased risk of incident depression; history of or risk factors for QT prolongation, osteoporosis. Men at risk of developing ureteric obstruction or spinal cord compression. Preexisting DM; known depression, HTN; MI, cardiac failure; reduced bone mineral density. Monitor for signs or symptoms of abdominal haemorrhage. Patients w/ low BMI &/or receiving full anticoagulation medications. Chronic alcohol abusers, smokers. Positive reactions in anti-doping tests. Long-term therapy w/ anticonvulsants or corticosteroids. Concomitant use w/ medicinal products prolonging QT interval; anti-androgens. Not to be used during pregnancy. Not recommended during lactation. Not to be used in childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Decreased libido; hot flush; hyperhidrosis; inj site reactions. Impaired glucose tolerance; mood changes, depression; paraesthesia; abnormal BP; rash; bone pain; decreased bone density, increased wt. Men: Erectile dysfunction. Spinal cord compression; cardiac failure, MI; gynaecomastia. Women: Acne; vulvovag dryness, breast enlargement. Headache; alopecia; arthralgia; tumour flare & pain.

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Drug Interactions

Drugs prolonging QT interval or inducing Torsade de pointes eg, class IA or III antiarrhythmics, methadone, moxifloxacin, antipsychotics.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Zoladex LA detailed prescribing information

Storage

View Zoladex LA storage conditions for details to ensure optimal shelf-life.

Description

View Zoladex LA description for details of the chemical structure and excipients (inactive components).

Action

View Zoladex LA mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Cancer Hormone Therapy / Trophic Hormones & Related Synthetic Drugs

ATC Classification

L02AE03 - goserelin ; Belongs to the class of gonadotropin releasing hormone analogues. Used in endocrine therapy.

Regulatory Classification

Patient Counseling Information

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Presentation/Packing

Form

Zoladex LA depot inj 10.8 mg

Packing/Price

1's

Zoladex LA

goserelin

Manufacturer:

AstraZeneca

Distributor:

Zuellig Pharma