Not a curative treatment for angina attacks or as initial treatment for unstable angina, MI, pre-hospital phase or during 1st days of hospitalisation. Discontinue use if movement disorders eg, parkinsonian symptoms, restless leg syndrome, tremors, gait instability occur. Falls related to gait instability or hypotension. +ve result in anti-doping tests. Not to be taken by patients w/ fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase insufficiency. May affect ability to drive & use machines. Moderate renal impairment. Avoid use during pregnancy. Not to be used during lactation. Childn <18 yr. Elderly >75 yr.