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Indications and Dosage
Oral
Dysmenorrhoea, Gastrointestinal tract spasm, Postoperative pain, Tenesmus, Urinary tract and bile stone colic, Visceral spasms Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid. Parenteral Dysmenorrhoea, Gastrointestinal tract spasm, Urinary tract and bile stone colic, Visceral spasms Adult: 8-16 mg daily, via IM or IV inj.
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Contraindications
Narrow angle glaucoma, benign prostatic hyperplasia, paralytic ileus, pyloric stenosis, ulcerative colitis, megacolon, tachyarrhythmia. Severe hepatic and renal impairment.
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Special Precautions
May impair ability to drive or operate machinery at high doses.
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Adverse Reactions
Dry mouth, blurring of vision, difficulty in swallowing and talking, constipation, urinary retention, mydriasis, arrhythmias.
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Drug Interactions
Increased antimuscarinic side effects with drugs with antimuscarinic properties e.g. amantadine, antihistamines, phenothiazide antipsychotics, TCAs. Antagonise GI effects of domperidone, metoclopramide. Delayed gastric emptying reduces absorption of other drugs.
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Action
Description:
Mechanism of Action: A quaternary ammonium anticholinergic with peripheral actions close to those of atropine. |
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Storage
Store below 25°C.
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MIMS Class
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