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Prelica

Prelica

pregabalin

Manufacturer:

Duopharma (M)

Distributor:

Duopharma Marketing
Concise Prescribing Info
Contents
Pregabalin
Indications/Uses
Peripheral & central neuropathic pain in adults. Adjunctive therapy in adults w/ partial seizures w/ or w/o secondary generalization. Generalized anxiety disorder (GAD). Management of fibromyalgia.
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Dosage/Direction for Use
150-600 mg daily in 2 or 3 divided doses. Neuropathic pain Initially 150 mg daily in 2 or 3 divided doses, may be increased to 300 mg daily after 3-7 days interval. Max: 600 mg daily after an additional 7-day interval. Fibromyalgia 300-450 mg daily in 2 divided doses. Start w/ 75 mg bd, may be increased to 150 mg bd w/in 1 wk or further increased to 225 mg bd. Max: 600 mg daily after an additional wk. Epilepsy Initially 150 mg daily in 2 or 3 divided doses, may be increased to 300 mg daily after 1 wk. Max: 600 mg daily after an additional wk. GAD 150-600 mg daily in 2 or 3 divided doses. Start w/ 150 mg daily, may be increased to 300 mg daily after 1 wk & 450 mg daily following an additional wk. Max: 600 mg daily after an additional wk.
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Overdosage
View Prelica overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity.
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Special Precautions
Hypersensitivity. Diabetes, CHF. Monitor for signs of suicidal ideation & behaviours. Patients w/ underlying conditions that may precipitate encephalopathy; history of substance abuse. Reduced lower GI tract function. W/drawal symptoms. Concomitant use w/ anti-epileptic & spasticity agents. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Renal impairment & failure. Women of childbearing potential should use effective contraception. Not to be used during pregnancy. Lactation. Not recommended for use in childn <12 yr. Elderly >65 yr.
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Adverse Reactions
Dizziness, somnolence, headache. Nasopharyngitis; increased appetite; euphoric mood, confusion, irritability, disorientation, insomnia, decreased libido; ataxia, abnormal coordination, tremor, dysarthria, amnesia, memory impairment, disturbance in attention, paraesthesia, hypoaesthesia, sedation, balance disorder, lethargy; blurred vision, diplopia; vertigo; vomiting, nausea, constipation, diarrhoea, flatulence, abdominal distension, dry mouth; muscle cramp, arthralgia, back & limb pain, cervical spasm; erectile dysfunction; peripheral oedema, oedema, abnormal gait, fall, feeling drunk & abnormal, fatigue; increased wt.
Drug Interactions
Potentiated effects of ethanol & lorazepam. Additive impairment of cognitive & gross motor function caused by oxycodone.
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Storage
View Prelica storage conditions for details to ensure optimal shelf-life.
Description
View Prelica description for details of the chemical structure and excipients (inactive components).
Action
View Prelica mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Anticonvulsants / Drugs for Neuropathic Pain
ATC Classification
N02BF02 - pregabalin ; Belongs to the class of gabapentinoids. Used to relieve pain and other conditions.
Presentation/Packing
Form
Prelica 150 mg cap
Packing/Price
10 × 10's;3 × 10's;6 × 10's
Form
Prelica 75 mg cap
Packing/Price
10 × 10's;3 × 10's;6 × 10's
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