Pneumovax 23

Purified capsular polysaccharides from the 23 most prevalent invasive pneumococcal types

Immunisation against pneumococcal disease caused by those pneumococcal types included in the vaccine. Immunocompetent individuals ≥2 yr: Person w/ chronic CV disease, chronic pulmonary disease or DM, alcoholism, chronic liver disease or CSF leaks, functional or anatomical asplenia; person living in special environments or social settings; routine vaccination for person ≥50 yr. Immunocompromised individuals ≥2 yr including those w/ HIV infection, leukemia, lymphoma, Hodgkin's disease, multiple myeloma, generalized malignancy, chronic renal failure or nephrotic syndrome; those receiving immunosuppressive chemotherapy & have received an organ or bone marrow transplant. Revaccination in person ≥2 yr at high risk of serious pneumococcal infection & those likely to have a rapid decline in pneumococcal Ab levels after at least 5 yr of 1st dose of pneumococcal vaccine.

Single 0.5 mL dose SC or IM (preferably in deltoid muscle or lateral mid-thigh).

Hypersensitivity. Epinephrine inj (1:1,000) must be immediately available should an acute anaphylactoid reaction occur.

Not to be inj IV or intradermally. Avoid intravascular administration. Expected serum Ab response may not be obtained in person receiving immunosuppressive therapy. Severely compromised CV &/or pulmonary function. Delay usage in febrile resp illness or other active infection. Antibiotic prophylaxis against pneumococcal infection should not be discontinued after vaccination w/ Pneumovax 23 when required. Avoid vaccination during chemo- or radiation therapy. Pregnancy & lactation. Not recommended in childn <2 yr. Frail elderly individuals w/ multiple co-morbid conditions.

Inj site reactions eg, soreness, erythema, warmth, swelling & local induration; decreased limb mobility; peripheral edema. Fever (≤38.8°C/102°F); asthenia/fatigue; myalgia; headache.

Vaccines, Antisera & Immunologicals

J07AL01 - pneumococcus, purified polysaccharides antigen ; Belongs to the class of pneumococcal bacterial vaccines.

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