Pharmaniaga Noradrenaline Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Noradrenaline bitartrate

Indications/Uses

BP control in acute hypotensive states eg, pheochromocytomectomy, sympathectomy, poliomyelitis, spinal anaesth, MI, septicaemia, blood transfusion & drug interactions. Adjunctive treatment of cardiac arrest & profound hypotension.

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Dosage/Direction for Use

Acute hypotensive states Initially 2-3 mL/min IV infusion. Maintenance: 0.5-1 mL/min. Duration: Up to 6 days.

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Overdosage

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Contraindications

Patients hypotensive from blood vol deficits; mesenteric or peripheral vascular thrombosis; profound hypoxia or hypercarbia. Concomitant use w/ cyclopropane & halothane anaesth.

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Warnings

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Special Precautions

Occlusive vascular diseases eg, atherosclerosis, arteriosclerosis, diabetic endarteritis, Buerger's disease. Monitor BP during treatment. Avoid abrupt w/drawal. Prolonged use. Avoid catheter tie-in technique; extravasation into tissues. Avoid contact w/ alkalis & oxidising agents. Patients receiving MAOIs or triptyline- or imipramine-type antidepressants. Pregnancy & lactation. Avoid inj into leg veins of elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Ischaemic injury; bradycardia, arrhythmias; anxiety, transient headache; resp difficulty; extravasation necrosis at inj site.

Drug Interactions

Increased cardiac autonomic irritability w/ cyclopropane & halothane anaesth. Severe, prolonged HTN w/ MAOIs or triptyline- or imipramine-type antidepressants. Incompatible w/ alkalis & oxidising agents, barbiturates, chlorpheniramine, chlorothiazide, nitrofurantoin, novobiocin, phenytoin, Na bicarbonate, Na iodide, streptomycin, sulfadiazine, sulfafurazole.

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Storage

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Description

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Action

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MIMS Class

Vasoconstrictors

ATC Classification

C01CA03 - norepinephrine ; Belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding glycosides. Used in the treatment of hypotension.

Regulatory Classification

Presentation/Packing

Form

Pharmaniaga Noradrenaline soln for inj 1 mg/mL

Packing/Price

4 mL x 1's

Pharmaniaga Noradrenaline

norepinephrine

Manufacturer:

Pharmaniaga LifeScience

Distributor:

Pharmaniaga Logistics