Duodenal & benign gastric ulcers 20 mg once daily for 4-8 wk, may be increased to 40 mg once daily for 4 wk.
Long-term therapy for recurrent duodenal ulcer 20 mg once daily for 1 yr.
Prevention of duodenal ulcer disease relapse 10 mg once daily, may be increased to 20-40 mg once daily.
Reflux oesophagitis 20 mg once daily for 4-8 wk.
Severe reflux oesophagitis 40 mg once daily for 8 wk.
Management of healed reflux oesophagitis 10 mg once daily, may be increased to 20-40 mg once daily.
Zollinger-Ellison syndrome Initially 60 mg once daily. Dose range: 20-120 mg tds.
H pylori-associated PUD Usual dose: 40 mg w/ amoxicillin 1.5 g daily (given as 750 mg bd) for 2 wk.
Hepatic impairment 10-20 mg daily.
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