Discontinue use if allergic or anaphylactic type reactions & 1st clinical signs of CV overload occur. Hypervolaemia or haemodilution (eg, decompensated cardiac insufficiency, HTN, oesophageal varices, pulmonary oedema, haemorrhagic diathesis, severe anemia, renal & post-renal anuria). Ensure adequate hydration. Monitor electrolytes status & circulatory overload or hyperhydration. In large vol replacement, ensure adequate substitution of other blood constituents (coagulation factors, electrolytes, platelets & erythrocytes). Controlled Na diet. Possibility of transmitting infective agents. Pregnancy.
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