Goutric

Goutric

febuxostat

Manufacturer:

Novugen Pharma

Distributor:

Novugen Pharma
Concise Prescribing Info
Contents
Febuxostat
Indications/Uses
Chronic hyperuricaemia in conditions where urate deposition has already occurred including history or presence of tophus &/or gouty arthritis.
Dosage/Direction for Use
Adult Recommended dose: 40 or 80 mg once daily. Initially 40 mg once daily. May be increased to 80 mg once daily if serum uric acid >6 mg/dL after 2-4 wk. Gout flare prophylaxis At least 6 mth therapy.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Discontinue use if allergic/hypersensitivity reactions including life-threatening SJS, TEN, acute anaphylactic reaction/shock occurs. Not to be initiated until acute gout attack subsides completely. Avoid use in patients w/ pre-existing major CV diseases eg, MI, stroke or unstable angina. Not recommended in patients w/ greatly increased rate of urate formation; in organ transplant recipients. Exacerbation &/or onset of CV disease; thyroid function alteration. Perform LFT prior to & periodically thereafter. Not to be taken by patients w/ galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Not recommended in concomitant use w/ mercaptopurine/azathioprine. May affect ability to drive & use machines. Severe renal & moderate to severe hepatic impairment. Not to be used during pregnancy & lactation. Childn <18 yr.
Adverse Reactions
Gout flares; headache; diarrhoea, nausea; liver function abnormalities; rash; oedema.
Drug Interactions
Increased plasma conc w/ mercaptopurine/azathioprine. Affected elimination w/ NSAIDs, probenecid. Increased metabolism & decreased efficacy by potent UGT inducers.
MIMS Class
Hyperuricemia & Gout Preparations
ATC Classification
M04AA03 - febuxostat ; Belongs to the class of preparations inhibiting uric acid production. Used in the treatment of gout.
Presentation/Packing
Form
Goutric FC tab 40 mg
Packing/Price
1 × 10's;10 × 10's;3 × 10's;5 × 10's
Form
Goutric FC tab 80 mg
Packing/Price
1 × 10's;10 × 10's;3 × 10's;5 × 10's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in