Discontinue use if allergic/hypersensitivity reactions including life-threatening SJS, TEN, acute anaphylactic reaction/shock occurs. Not to be initiated until acute gout attack subsides completely. Avoid use in patients w/ pre-existing major CV diseases eg, MI, stroke or unstable angina. Not recommended in patients w/ greatly increased rate of urate formation; in organ transplant recipients. Exacerbation &/or onset of CV disease; thyroid function alteration. Perform LFT prior to & periodically thereafter. Not to be taken by patients w/ galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Not recommended in concomitant use w/ mercaptopurine/azathioprine. May affect ability to drive & use machines. Severe renal & moderate to severe hepatic impairment. Not to be used during pregnancy & lactation. Childn <18 yr.