Cap Adult 600-1,800 mg daily in 2, 3 or 4 equal doses.
Childn from 2 yr 8-25 mg/kg daily in 3 or 4 equal doses.
β-hemolytic streptococcal infections Continue treatment for at least 10 days.
Chlamydia trachomatis cervicitis 450 mg qds for 10-14 days.
Toxoplasmic encephalitis in patient w/ AIDS 600-1,200 mg 6 hrly IV/PO for 2 wk followed by 300-600 mg PO 6 hrly. Duration: 8-10 wk. Pyrimethamine dose: 25-75 mg PO daily for 8-10 wk. Folinic acid dose: 10-20 mg daily.
Pneumocystis jiroveci in patient w/ AIDS 600-900 mg 6 hrly or 900 mg 8 hrly IV or 300-450 mg PO 6 hrly for 21 days. Primaquine dose: 15-30 mg PO once daily for 21 days.
Acute streptococcal tonsillitis/pharyngitis 300 mg bd for 10 days.
IM/IV Adult Serious infection 2,400-2,700 mg daily in 2, 3 or 4 equal doses.
Less complicated infections 1,200-1,800 mg daily in 3 or 4 equal doses. Max dose: 4,800 mg daily. Single IM doses of >600 mg are not recommended.
Pelvic inflammatory disease 900 mg 8 hrly w/ gm -ve aerobic antibiotic, continue w/ 450-600 mg PO 6 hrly to complete 10-14 days of therapy.
Childn from 2 yr 20-40 mg/kg daily in 3 or 4 equal doses.
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