Generic Medicine Info
Indications and Dosage
Adult: 0.2-1 g at night.
Elderly and debilitated patients; young adults, child; depression; pulmonary insufficiency; sleep apnoea; preexisting CNS depression or coma; severe hepatic impairment. Porphyria. Pregnancy and lactation. Elderly and debilitated patients; young adults and childn.
Special Precautions
Renal insufficiency; may cause paradoxical excitatory reaction when given to patients in pain unless an analgesic is given concomitantly; may impair ability to drive or operate machinery.
Adverse Reactions
Dependence; drowsiness, sedation, ataxia; resp depression; headache; GI disturbances; skin reactions; confusion and memory defects; paradoxical excitement, irritability; hypersensitivity reactions; haematologic disorders. Nystagmus, miosis, slurred speech and ataxia in excessive doses.
Potentially Fatal: Bromide accumulation and symptoms resembling bromism. Produces neonatal intoxication, vit K deficiency symptoms, congenital malformations when taken during pregnancy.
Drug Interactions
Sedation or resp depression may be enhanced by drugs with CNS depressants; MAOIs may prolong the CNS depressant effects and also reduce the convulsive threshold, thereby antagonise the anticonvulsant action of barbiturates. Others: Fenoprofen, methadone, pethidine and opioid analgesics; disopyramide, lidocaine and quinidine; chloramphenicol, doxycycline; warfarin and coumarin; antidepressants eg, bupropion, fluoxetine, lithium and mianserin; valproate and progabide; vigabatrin, oxcarbazepine, carbamazepine, clonazepam, ethosuximide, lamotrigine, tiagabine and zonisamide, griseofulvin; teniposide; metronidazole; chlorpromazine; HIV-protease inhibitors; β-blockers; calcium-channel blockers eg, nifedipine and verapamil; digitoxin; ciclosporin; corticosteroids; furosemide; montelukast; oral contraceptives; theophylline; levothyroxine; influenza vaccination and vitamins. Alcohol. St. John's wort.
Mechanism of Action: Bromisoval has actions and uses similar to carbromal, a bromureide which in turn have general properties similar to barbiturates. It was formerly used for its sedative and hypnotic properties.
MIMS Class
Hypnotics & Sedatives
Disclaimer: This information is independently developed by MIMS based on Bromisoval from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by
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