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Indications and Dosage
Oral
Pain and inflammation associated with musculoskeletal and joint disorders Adult: 60 mg tid or 120 mg as a single daily dose.
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Administration
Should be taken with food. Take w/ or immediately after meals.
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Special Precautions
Pregnancy, lactation.
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Adverse Reactions
Adverse GI effects, anorexia, vomiting, diarrhoea, constipation. Anaemia, leucopenia, thrombocytopenia.
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Drug Interactions
Possible increased risk of seizures when used with ciprofloxacin and norfloxacin. May also increase serum levels of warfarin, methotrexate, lithium salts and sulphonylurea derivatives.
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Action
Description:
Mechanism of Action: Loxoprofen is a non-selective cyclooxygenase inhibitor. It works by reducing the synthesis of prostaglandins from arachidonic acid. It is a prodrug that is rapidly converted to its active metabolite after oral admin. |
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