Contraindications
Hypersensitivity; infectious mononucleosis; lymphatic leukaemia; HIV infection.
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Special Precautions
Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Avoid contact, skin sensitization may occur. Monitor serum K concentration, renal and hematological status. Spirochete infections particularly syphilis; suprainfection with penicillin-resistant organisms with prolonged use; avoid intrathecal route.
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Adverse Reactions
Hypersensitivity reactions including uticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; haemolytic anaemia; interstitial nephritis; neutropaenia; thrombocytopaenia; CNS toxicity including convulsions; antibiotic-associated colitis. GI effects; pseudomembranous colitis; erythematous maculopapular erruptions.
Potentially Fatal: Anaphylaxis. |
Drug Interactions
Probenecid prolongs T
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Lab Interference
May interfere with diagnostic tests for urinary glucose using copper sulfate, direct Coomb's test, and test for urinary or serum proteins. May interfere with diagnostic tests that use bacteria.
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Action
Description:
Mechanism of Action: Hetacillin is a β-lactam antibiotic which is converted in the body to ampicillin and has action similar to those of ampicillin. |
MIMS Class
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