Primary biliary cirrhosis Adult & elderly 10-15 mg/kg/day in 2-4 divided doses.
Dissolution of gallstones Adult & elderly 6-12 mg/kg/day either as a single night time dose or in divided doses. May be increased to 15 mg/kg/day in obese patients, if necessary. Duration: May be up to 2 yr & should be continued for 3 mth after apparent dissolution of the stones.