S-Oropram

Escitalopram oxalate

Major depressive disorders.

10 mg daily, may be increased to 20 mg daily. Elderly Max: 10 mg daily.

May be taken with or without food.

Hypersensitivity. Concomitant use w/ MAOIs. QT interval prolongation or congenital long QT syndrome.

Paradoxical anxiety, seizures, mania, diabetes, suicide/suicidal thoughts, akathisia/psychomotor restlessness, hyponatremia, haemorrhage, electroconvulsive therapy, serotonin syndrome, discontinuation symptoms, coronary heart disease, QT interval prolongation. Concomitant w/ SSRIs & St John's wort. Hepatic impairment. May affect ability to drive or operate machinery. Pregnancy & lactation. Childn <18 yr.

Nausea. Decreased/increased appetite, anxiety, restlessness, abnormal dreams, decreased libido, anorgasmia, insomnia, somnolence, dizziness, paraesthesia, tremor, sinusitis, yawning, diarrhoea, constipation, vomiting, dry mouth, increased sweating, arthralgia, myalgia, ejaculation disorder, impotence, fatigue, pyrexia, wt gain.

Serious reactions w/ MAOIs ie, moclobemide, linezolid, selegiline. Increased conc w/ CYP2C19 & cimetidine. Concomitant w/ tramadol, sumatriptan & other triptans may lead to serotonin syndrome. Decreased seizure threshold w/ TCAs, SSRIs, neuroleptics, mefloquine, bupropion. Lithium, tryptophan. Altered anticoagulant effects. Flecainide, propafenone, metoprolol, desipramine, clomipramine, nortriptyline, risperidone, thioridazine, haloperidol, class IA & III antiarryhthmics, ziprasidone, methadone, moxifloxacin, diuretics, laxatives, enemas, amphotericin B, corticosteroids (high dose). Wait until 24 hr after the last dose of linezolid.

Antidepressants

N06AB10 - escitalopram ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.

P₁S₁S₃